Cephalexin is used as an anti-biotic. It is poorly soluble in water with erratic oral absorption and bioavailability less than 70%. More over cephalexin has a narrow therapeutic range and shows bioavailbility differences. In efforts to reduce the frequency of dosing required for chronic urinary tract infections and to decrease variability in plasma concentration, cephalexin can be formulated into controlled release systems. Even though several controlled release polymers are available, there is continuous need to develop safe, economical and biodegradable controlled release polymers. Hence, in the present investigation an attempt was made to develop a new controlled release polymer i.e., Azadirachta indica gum.
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